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CodY of<i>Streptococcus pneumoniae</i>: Link between Nutritional Gene Regulation and Colonization

17 Nov 2007

Abstract excerpt

CodY is a nutritional regulator mainly involved in amino acid metabolism. It has been extensively studied in Bacillus subtilis and Lactococcus lactis. We investigated the role of CodY in gene regulation and virulence of the human pathogen Streptococcus pneumoniae. We constructed a codY mutant and examined the effect on gene and protein expression by microarray and two-dimensional differential gel electrophoresis...

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Identifiers

PMID: 18024519
DOI: 10.1128/jb.00917-07

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