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Article

Neocortical atrophy in Machado-Joseph disease: a longitudinal neuroimaging study.

Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Jul 2012

D'Abreu Anelyssa, França Marcondes C, Yasuda Clarissa L, Campos Bruno A G, Lopes-Cendes Iscia, Cendes Fernando

Abstract excerpt

BACKGROUND/PURPOSE: Previous imaging studies in the Machado-Joseph disease (MJD/SCA3) have mostly concentrated on the cerebellum and brainstem. Our goal was to perform a whole brain longitudinal evaluation. METHODS: We included 45 patients and 51 controls, who underwent two brain magnetic resonance imaging and magnetic resonance spectroscopy (mean interval of 12.5 ± 1.5 months). We used voxel-based morphometry...

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Identifiers

PMID: 21699609
DOI: 10.1111/j.1552-6569.2011.00614.x

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