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Article

A voxel-based morphometry study of grey matter loss in fragile X-associated tremor/ataxia syndrome.

Brain : a journal of neurology - 1 Mar 2011

Hashimoto Ryu-ichiro, Javan Alireza K, Tassone Flora, Hagerman Randi J, Rivera Susan M

Abstract excerpt

Fragile X-associated tremor/ataxia syndrome is a neurodegenerative disorder that primarily affects older male premutation carriers of the fragile X mental retardation gene. Although its core symptoms are mainly characterized by motor problems such as intention tremor and gait ataxia, cognitive decline and psychiatric problems are also commonly observed. Past radiological and histological approaches have focused...

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Identifiers

PMID: 21354978
DOI: 10.1093/brain/awq368
PMCID: PMC3044831

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