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Article

Brain structural damage in Friedreich's ataxia.

Journal of neurology, neurosurgery, and psychiatry - 1 Jan 2008

Della Nave R, Ginestroni A, Giannelli M, Tessa C, Salvatore E, Salvi F, Dotti M T, De Michele G, Piacentini S, Mascalchi M

Abstract excerpt

OBJECTIVE: Neuropathological descriptions of the brain in Friedreich's ataxia (FRDA) were obtained before availability of the current molecular genetic tests for this disease. Voxel-based morphometry (VBM) enables an unbiased whole-brain quantitative analysis of differences in gray matter (GM) and white matter (WM) volume. METHODS: Using VBM, we assessed the brain structural damage in 22 patients with genetically...

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Source

Identifiers

PMID: 17634216
DOI: 10.1136/jnnp.2007.124297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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