Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences.

Abstract excerpt

The genome-sequencing gold rush has facilitated the use of comparative genomics to uncover patterns of genome evolution, although their causal mechanisms remain elusive. One such trend, ubiquitous to prokarya and eukarya, is the association of insertion/deletion mutations (indels) with increases in the nucleotide substitution rate extending over hundreds of base pairs. The prevailing hypothesis is that indels are...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteria
• Share to DNA-Directed DNA Polymerase
• Share to DNA Repair Enzymes