Article
HLAsupE: an integrated database of HLA supertype-specific epitopes to aid in the development of vaccines with broad coverage of the human population.
BMC immunology - 16 Jun 2016
Wang Shufeng, Guo Ling, Liu Dong, Liu Wei, Wu Yuzhang
Abstract excerpt
BACKGROUND: Promiscuous T-cell epitopes that can be presented by multiple human leukocyte antigens (HLAs) are prime targets for vaccine and immunotherapy development because they are effective in a high proportion of the human population. Although there are a number of epitope databases currently available online, the epitope data in these databases were annotated using specific MHC restrictions, and none of...
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