Article
Mapping genetic loci that interact with myostatin to affect growth traits.
Heredity - 1 Dec 2011
Cheng Y, Rachagani S, Dekkers J C M, Mayes M S, Tait R, Reecy J M
Abstract excerpt
Myostatin, or GDF8, is an inhibitor of skeletal muscle growth. A non-functional myostatin mutation leads to a double muscling phenotype in some species, for example, mice, cattle and humans. Previous studies have indicated that there are loci in the genome that interact with myostatin to control backfat depth and other complex traits. We now report a quantitative trait loci (QTL) mapping study designed to...
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