Article
Interval mapping of high growth (hg), a major locus that increases weight gain in mice.
Genetics - 1 Apr 1995
Horvat S, Medrano J F
Abstract excerpt
The high growth locus (hg) causes a major increase in weight gain and body size in mice. As a first step to map-based cloning of hg, we developed a genetic map of the hg-containing region using interval mapping of 403 F2 from a C57BL/6J-hghg x CAST/EiJ cross. The maximum likelihood position of hg...
Topics
- Alleles
- Animals
- Base Sequence
- Chromosome Mapping
- Crosses, Genetic
- DNA Primers
- Decorin
- Extracellular Matrix Proteins
- Female
- Genetic Markers
- Insulin-Like Growth Factor I
- Lod Score
- Male
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Phenotype
- Proteoglycans
