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Article

Interval mapping of high growth (hg), a major locus that increases weight gain in mice.

Genetics - 1 Apr 1995

Horvat S, Medrano J F

Abstract excerpt

The high growth locus (hg) causes a major increase in weight gain and body size in mice. As a first step to map-based cloning of hg, we developed a genetic map of the hg-containing region using interval mapping of 403 F2 from a C57BL/6J-hghg x CAST/EiJ cross. The maximum likelihood position of hg was at the chromosome 10 marker D10Mit41 (LOD = 24.8) in the F2 females and 1.5 cM distal to D10Mit41 (LOD = 9.56) in...

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Identifiers

PMID: 7789774
DOI: 10.1093/genetics/139.4.1737
PMCID: PMC1206499

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