Article
Inferring causative variants in microRNA target sites.
Nucleic acids research - 1 Sept 2011
Thomas Laurent F, Saito Takaya, Sætrom Pål
Abstract excerpt
MicroRNAs (miRNAs) regulate genes post transcription by pairing with messenger RNA (mRNA). Variants such as single nucleotide polymorphisms (SNPs) in miRNA regulatory regions might result in altered protein levels and disease. Genome-wide association studies (GWAS) aim at identifying genomic regions that contain variants associated with disease, but lack tools for finding causative variants. We present a...
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