Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prediction of the biological effect of polymorphisms within microRNA binding sites.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Landi Debora, Barale Roberto, Gemignani Federica, Landi Stefano

Abstract excerpt

MicroRNAs (miRNAs) are negative gene regulators acting at the 3'UTR level, modulating the translation of cancer-related genes. Single-nucleotide polymorphisms (SNPs) within the 3'UTRs could impact the miRNA-dependent gene regulation either by weakening or by reinforcing the binding sites. Thus, the alteration of the normal regulation of a given gene could affect the individual's risk of cancer. Therefore, it is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Algorithms
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to MicroRNAs

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 20931399
DOI: 10.1007/978-1-60761-863-8_14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prediction of the biological effect of polymorphisms within microRNA binding sites.PMID 20931399Read ↗

mrSNP: software to detect SNP effects on microRNA binding.Semantic proximity Read ↗

A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites.Semantic proximity Read ↗

A catalog of polymorphisms falling in microRNA-binding regions of cancer genes.Semantic proximity Read ↗

Single nucleotide polymorphisms in microRNA binding sites: implications in colorectal cancer.Semantic proximity Read ↗

SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers.Semantic proximity Read ↗

MicroRNA binding site polymorphisms as biomarkers of cancer risk.Semantic proximity Read ↗

The role of microRNAs in cancer susceptibility.Semantic proximity Read ↗

Natural selection on human microRNA binding sites inferred from SNP data.Semantic proximity Read ↗

Genetic variations in microRNA-binding sites of solute carrier transporter genes as predictors of clinical outcome in colorectal cancer.Semantic proximity Read ↗

Inferring single nucleotide polymorphisms in microRNA binding sites of lung cancer-related inflammatory genes.Semantic proximity Read ↗

MicroRNA binding-site polymorphisms as potential biomarkers of cancer risk.Semantic proximity Read ↗

Single nucleotide polymorphisms in microRNA binding sites of oncogenes: implications in cancer and pharmacogenomics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.