Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the AKR gene locus AKv-1 in susceptibility to chemical induction of thymic lymphomas.

Cancer research - 1 Oct 1990

Becker F F

Abstract excerpt

Various strains of mice demonstrate widely differing susceptibility to chemical induction of thymic lymphomas, in both timing and incidence. In AKR mice tumors appear very early and at high incidence after a single dose of N-methyl-N-nitrosourea, while in other strains they appear later and at lower incidences. In an attempt to determine the potential role of AKR ecotropic murine leukemia virus loci in this...

Topics

Alleles
Animals
Disease Susceptibility
Female
Genes, Viral
Leukemia Virus, Murine
Lymphoma
Methylnitrosourea
Mice
Mice, Inbred AKR
Organ Size
Thymus Gland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thymus Neoplasms

Source

Identifiers

PMID: 2169341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2169341-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Role of the AKR gene locus AKv-1 in susceptibility to chemical induction of thymic lymphomas.PMID 2169341Read ↗

Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea.Semantic proximity Read ↗

The mutagenic response at the ouabain resistance locus in T cells of mice exposed to N-ethyl-N-nitrosourea parallels the response at the Hprt locus and correlates with mutation target size.Semantic proximity Read ↗

Influence of sex and carcinogen treatment protocol on tumor latency and frequency of K-ras mutations in N-methyl-N-nitrosourea-induced lymphomas.Semantic proximity Read ↗

Observations on lymphomagenesis and lymphoma in AKR mice. A description of prelymphoma changes in the thymus and phenotypic diversity of lymphomas induced by SL3-3 virus.Semantic proximity Read ↗

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.Semantic proximity Read ↗

N-Ethyl-N-nitrosourea induces mammary cancers in the pituitary-isografted mouse which are histologically and genotypically distinct from those induced by N-methyl-N-nitrosourea.Semantic proximity Read ↗

Genetic regulation of development of thymic lymphomas induced by N-propyl-N-nitrosourea in the rat.Semantic proximity Read ↗

Differential up-regulation of H-2D versus H-2K class I major histocompatibility expression by interferon-gamma: evidence against a trans-acting allele-specific factor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.