Inhibition of phosphorylation of cellular dUTP nucleotidohydrolase as a consequence of herpes simplex virus infection.

doi:10.1002/jcb.240430406

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Article

Inhibition of phosphorylation of cellular dUTP nucleotidohydrolase as a consequence of herpes simplex virus infection.

Journal of cellular biochemistry - 1 Aug 1990

Lirette R, Caradonna S

Abstract excerpt

During an infection with herpes simplex virus, activity of cellular dUTPase decreases as a function of time, post-infection, while virus-encoded dUTPase activity increases. Prelabeling of cells with 35S-methionine and immunoprecipitation analysis, using monoclonal antibodies, indicates that cellu...

Topics

HeLa Cells
Humans
Mutation
Phosphorylation
Precipitin Tests
Protein Processing, Post-Translational
Pyrophosphatases
Restriction Mapping
Serine
Simplexvirus

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