Article
A mutant of herpes simplex virus type 1 in which the UL13 protein kinase gene is disrupted.
The Journal of general virology - 1 Mar 1993
Coulter L J, Moss H W, Lang J, McGeoch D J
Abstract excerpt
Gene UL13 of herpes simplex virus type 1 (HSV-1) has previously been proposed to encode a protein kinase. An HSV-1 mutant with UL13 inactivated by insertion of the Escherichia coli lacZ gene was constructed. This UL13-lacZ mutant was found to grow to near wild-type (wt) titres in tissue culture. Comparison of silver-stained SDS-PAGE profiles of wt and UL13-lacZ virions demonstrated that the UL13 protein is a...
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