Article
Replication properties of dUTPase-deficient mutants of caprine and ovine lentiviruses.
Journal of virology - 1 Feb 1996
Turelli P, Pétursson G, Guiguen F, Mornex J F, Vigne R, Quérat G
Abstract excerpt
The virion-associated dUTPase activities of caprine arthritis-encephalitis virus (CAEV) and visna virus were determined by using an assay which measure the actual ability of the dUTPase to prevent the dUTP misincorporations into cDNA during reverse transcription. We showed that the CAEV molecular clone from the Cork isolate was dUTPase defective as a result of a single amino acid substitution. Using this point...
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