Article
The role of CD23 in IgE dependent signaling: implications from pharmacogenetics.
Transactions of the American Clinical and Climatological Association - 1 Jan 2011
Rosenwasser Lanny J, Meng Jianfeng, Chan Marcia A, Gigliotti Nicole M, May Brianna E
Abstract excerpt
The association of immunoglobulin E (IgE) with allergic diseases and asthma is well established. IgE binds to two receptors on various immune and inflammatory cells. The lower-affinity IgE Fc receptor, CD23, has multiple functions in enhancing the regulation of IgE production itself, and that of various pro-inflammatory activities and mediators. The data in this report are derived from an analysis of variation in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
