Article
Increased levels of sCD23 in rheumatoid arthritis are related to disease status.
Clinical and experimental rheumatology - 1 Jan 2000
Bansal A S, MacGregor A J, Pumphrey R S, Silman A J, Ollier W E, Wilson P B
Abstract excerpt
The low affinity receptor for IgE (Fc epsilon RII, CD23) is involved in many aspects of T and B cell regulation. In the current study, serum levels of sCD23 were measured in monozygotic (MZ) twins discordant for rheumatoid arthritis (RA) to examine whether an increased level of sCD23 in RA is, at least in part, genetically determined. Paired analysis showed significantly elevated sCD23 levels in affected twins...
Topics
- Arthritis, Rheumatoid
- Enzyme-Linked Immunosorbent Assay
- Family Health
- Female
- Humans
- Luminescent Measurements
- Male
- Phenotype
- Receptors, IgE
- Solubility
- Twins, Monozygotic