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Article

Polymorphism R62W results in resistance of CD23 to enzymatic cleavage in cultured cells.

Genes and immunity - 1 Apr 2007

Meng J-F, McFall C, Rosenwasser L J

Abstract excerpt

A nonsynonymous single nucleotide polymorphism (SNP) of the low-affinity IgE receptor (FcvarepsilonRII/CD23) gene resulting in an arginine to tryptophan exchange at amino-acid position 62 (R62W) has been associated with enhanced T-cell responses to antigen in allergic subjects. To explore the mechanism, a CD23(a) cDNA was cloned into the plasmid pCMVScript-CD23a-C with a C allele (R62). The pCMVScript-CD23a-T...

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PMID: 17301828
DOI: 10.1038/sj.gene.6364376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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