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Article

A structurally conserved human and Tetrahymena telomerase catalytic core

23 Nov 2020

Abstract excerpt

Significance Among reverse transcriptases, telomerase reverse transcriptase (TERT) has the unique ability to replenish DNA repeats at chromosome ends by repetitively using its integral RNA template. TERT shares a variety of common features with other reverse transcriptases as well as telomerase-specific motifs/domains. Among them, TEN and TRAP are not obviously present in all annotated TERT sequences, yet they...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33229538
DOI: 10.1073/pnas.2011684117

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