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Article

Genetic analysis of lysosomal alpha-galactosidase A gene in sporadic Parkinson's disease.

Neuroscience letters - 1 Aug 2011

Wu Guanghua, Pang Shuchao, Feng Xungang, Zhang Aimei, Li Jifeng, Gu Kejin, Huang Jian, Dong Haixin, Yan Bo

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disease. Majority of PD cases are sporadic, resulting from interaction of genetic and environmental factors. Accumulating evidence indicates that autophagy, which delivers alpha-synuclein to lysosomes for degradation, is involved in the PD pathogenesis. Some lysosomal hydrolases, such as glucocerebrosidase gene and ATP13A2, a lysosomal ATPase gene, have...

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Source

Identifiers

PMID: 21683120
DOI: 10.1016/j.neulet.2011.05.238

Genes

GLA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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