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Article

A novel and functional variant within the ATG5 gene promoter in sporadic Parkinson's disease.

Neuroscience letters - 22 Mar 2013

Chen Dongfeng, Zhu Cuiping, Wang Xuenan, Feng Xungang, Pang Shuchao, Huang Wenhui, Hawley Robert G, Yan Bo

Abstract excerpt

Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Majority of PD are sporadic, for which genetic causes remain largely unknown. Alpha-synuclein, the main component of Lewy bodies, plays a central role in the PD pathogenesis. Macroautophagy is a highly conserved cellular process that digests dysfunctional macromolecules and damaged organelles. Accumulating evidence indicates that...

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Source

Identifiers

PMID: 23384565
DOI: 10.1016/j.neulet.2013.01.044

Genes

ATG5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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