Article
Genetic analysis of the ATG16L1 gene promoter in sporadic Parkinson's disease.
Neuroscience letters - 12 Apr 2017
Wang Lixia, Huang Jian, Pang Shuchao, Qin Xianyun, Qi Ziyou, Hawley Robert G, Yan Bo
Abstract excerpt
Parkinson's disease (PD) is a common and progressive neurodegenerative disease in which the majority of cases arise sporadically. Sporadic PD is caused by the interactions of genetic and environmental factors. To date, genetic causes for sporadic PD remain largely unknown. Autophagy, a highly conserved cellular process, has been implicated in PD pathogenesis. We speculated that genetic variants in...
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