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Article

Clinical-pathologic significance of cancer stem cell marker expression in familial breast cancers.

Breast cancer research and treatment - 1 Jul 2013

Bane Anita, Viloria-Petit Alicia, Pinnaduwage Dushanthi, Mulligan Anna Marie, O'Malley Frances P, Andrulis Irene L

Abstract excerpt

Human breast cancer cells with a CD44(+)/CD24(-/low) or ALDH1+ phenotype have been demonstrated to be enriched for cancer stem cells (CSCs) using in vitro and in vivo techniques. The aim of this study was to determine the association between CD44(+)/CD24(-/low) and ALDH1 expression with clinical-pathologic tumor characteristics, tumor molecular subtype, and survival in a well characterized collection of familial...

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Source

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Identifiers

PMID: 23813303
DOI: 10.1007/s10549-013-2591-1
PMCID: PMC3706716

Genes

BRCA1
BRCA2
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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