Article
Improvement in predicting tumorigenic phenotype of androgen-insensitive human LNCaP prostatic cancer cell subline in recombination with rat urogenital sinus mesenchyme.
Cancer science - 1 Dec 2008
Kanai Masahiro, Ishii Kenichiro, Kanda Hideki, Ogura Yuji, Kise Hideaki, Arima Kiminobu, Sugimura Yoshiki
Abstract excerpt
Hormone-refractory prostate cancer, a heterogeneous disease, has varying degrees of androgen sensitivity. To understand the physiological changes in the hormone-refractory state, the present study used a lineage-derived androgen receptor (AR)-positive, androgen-insensitive prostate cancer cell li...
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