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Article

In vitro propagation and characterization of neoplastic stem/progenitor‐like cells from human prostate cancer tissue

30 Jul 2009

Abstract excerpt

BACKGROUND: According to the cancer stem cell hypothesis, tumor growth is sustained by a subpopulation of cancer stem/progenitor-like cells. Self-renewal and high clonogenic potential are characteristics shared by normal stem and neoplastic stem/progenitor-like cells. We investigated whether human prostate cancer specimens contain cells with these properties. METHODS: Self-renewal and clonogenic potential were...

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PMID: 19644960
DOI: 10.1002/pros.21018

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