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Article

Characterization of PRNP and SPRN coding regions from atypical scrapie cases diagnosed in Poland.

Molecular biology reports - 1 Mar 2012

Piestrzyńska-Kajtoch Agata, Gurgul Artur, Polak Mirosław P, Smołucha Grzegorz, Zmudziński Jan F, Rejduch Barbara

Abstract excerpt

Scrapie, a fatal transmissible spongiform encephalopathy (TSE) occurs in two phenotypes: classical and atypical. Many authors point out that the polymorphism of three codons (136, 154, 171) of the PRNP (PrP gene) is associated with a sheep susceptibility to classical scrapie. Until now, only one PRNP gene variant coding phenylalanine at codon 141 has been found to be associated with atypical scrapie. Another...

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PMID: 21674189
DOI: 10.1007/s11033-011-1010-0

Genes

PRNP
SPRN

Variants

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Characterization of PRNP and SPRN coding regions from atypical scrapie cases diagnosed in Poland.PMID 21674189Read ↗

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