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Article

Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice

14 Jun 2011

Abstract excerpt

Alzheimer's disease is a neurodegenerative disorder of the elderly and advancing age is the major risk factor for Alzheimer's disease development. Telomere shortening represents one of the molecular causes of ageing that limits the proliferative capacity of cells, including neural stem cells. Studies on telomere lengths in patients with Alzheimer's disease have revealed contrary results and the functional role of...

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Share to Genetics, Aging, and Longevity in Model Organisms
Share to Neurogenesis and neuroplasticity mechanisms
Share to Telomeres, Telomerase, and Senescence

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PMID: 21672962
DOI: 10.1093/brain/awr133

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