Article
Nucleotide sequences of the VP1 capsid proteins of wild poliovirus types 1 and 3 from epidemic areas of Brazil.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 1990
Da-Silva E E, Schatzmayr H G, Kew O M
Abstract excerpt
The nucleotide sequences encoding the capsid protein VP1 were determined for the wild polioviruses of serotypes 1 and 3 endemic to the northeastern region of Brazil. Compared with the corresponding Sabin vaccine strain sequences, the wild isolates differed at 20% (type 1) and 22% (type 3) of their nucleotide positions, and in 7% (type 1) and 11% (type 3) of their amino acid residues. The highest degree of amino...
Topics
- Antigenic Variation
- Base Sequence
- Brazil
- Capsid
- Capsid Proteins
- Genes, Viral
- Molecular Sequence Data
- Mutation
- Poliomyelitis
- Poliovirus