Article
Poliovirus type 1 isolated from a vaccine-associated case of paralytic poliomyelitis in Brazil.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 1996
Friedrich F, Filippis A M, Ferreira F C, Oliveira M J, Schatzmayr H G, Da-Silva E E
Abstract excerpt
This study reports a type 1 poliovirus strain isolated in Brazil from a case classified as vaccine-associated paralytic poliomyelitis (VAPP). After serotyping of the viral isolate with hyperimmune equine sera, PCR and molecular hybridization techniques characterized the strain as P1/Sabin-derived. The isolate was partially sequenced to identify mutations at nucleotides 480, 525 and 6203, which are important for...
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