Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway.

Molecular and cellular biochemistry - 1 Dec 2011

Yang Weiwei, Zhang Jia, Wang Haiya, Gao Pingjin, Singh Manpreet, Shen Kai, Fang Ningyuan

Abstract excerpt

Angiotensin II (Ang II) plays a profound regulatory effect on NADPH oxidase and the functional features of vascular adventitial fibroblasts, but its role in antioxidant enzyme defense remains unclear. This study investigated the effect of Ang II on expressions and activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in adventitial fibroblasts and the possible mechanism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Aorta

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Catalase

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to Phosphoinositide-3 Kinase Inhibitors

Share to Polyethylene Glycols

Share to Receptor, Angiotensin, Type 1

Source

Identifiers

PMID: 21660462
DOI: 10.1007/s11010-011-0915-1

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway.PMID 21660462Read ↗

CREG mediated adventitial fibroblast phenotype modulation: a possible therapeutic target for proliferative vascular disease.Semantic proximity Read ↗

Redox Metabolism and Vascular Calcification in Chronic-Kidney DiseaseSemantic proximity Read ↗

Reduction of Superoxide Dismutase 1 Delays Regeneration of Cardiotoxin-Injured Skeletal Muscle in KK/Ta-Ins2Akita Mice with Progressive Diabetic Nephropathy.Semantic proximity Read ↗

Redox regulation of vascular smooth muscle cell differentiation.Semantic proximity Read ↗

Nrf2-dependent induction of NQO1 in mouse aortic endothelial cells overexpressing catalase.Semantic proximity Read ↗

Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction.Semantic proximity Read ↗

Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice.Semantic proximity Read ↗

Vascular endothelium-specific overexpression of human catalase in cloned pigsSemantic proximity Read ↗

Synthetic smooth muscle cell phenotype is associated with increased nicotinamide adenine dinucleotide phosphate oxidase activity: effect on collagen secretion.Semantic proximity Read ↗

Activity of antioxidant enzymes in children from families at high risk of premature coronary heart disease.Semantic proximity Read ↗

Unchanged NADPH Oxidase Activity in Nox1-Nox2-Nox4 Triple Knockout Mice: What Do NADPH-Stimulated Chemiluminescence Assays Really Detect?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.