Article
Sequence elements outside the catalytic core of natural hairpin ribozymes modulate the reactions differentially.
Biological chemistry - 1 Jul 2011
Bajaj Preeti, Steger Gerhard, Hammann Christian
Abstract excerpt
Abstract Hairpin ribozymes occur naturally only in the satellite RNAs of tobacco ringspot virus (TRsV), chicory yellow mottle virus (CYMoV) and arabis mosaic virus (ArMV). The catalytic centre of the predominantly studied sTRsV hairpin ribozyme, and of sArMV is organised around a four-way helical junction. We show here that sCYMoV features a five-way helical junction instead. Mutational analysis indicates that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
