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Article

Intermolecular interaction between a branching ribozyme and associated homing endonuclease mRNA.

Biological chemistry - 1 Apr 2011

Birgisdottir Ása B, Nielsen Henrik, Beckert Bertrand, Masquida Benoît, Johansen Steinar D

Abstract excerpt

RNA tertiary interactions involving docking of GNRA (N; any base; R; purine) hairpin loops into helical stem structures on other regions of the same RNA are one of the most common RNA tertiary interactions. In this study, we investigated a tertiary association between a GAAA hairpin tetraloop in a small branching ribozyme (DiGIR1) and a receptor motif (HEG P1 motif) present in a hairpin structure on a separate...

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PMID: 21495911
DOI: 10.1515/BC.2011.055

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