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Article

Self-cleavage of a 71 nucleotide-long ribozyme derived from hepatitis delta virus genomic RNA.

Nucleic acids research - 11 Dec 1991

Thill G, Blumenfeld M, Lescure F, Vasseur M

Abstract excerpt

Self-cleavage efficiency of ribozymes derived from hepatitis delta virus (HDV) has been shown to depend on the RNA structure, which in turn may be determined by the length of the considered sequences. Here we describe the construction and functional analysis of a 71 nucleotide-long RNA genomic fragment, Rz71, which carries an 18 nucleotide deletion in a very stable GC-rich stem-loop (stem IV), predicted to be...

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Identifiers

PMID: 1754389
DOI: 10.1093/nar/19.23.6519
PMCID: PMC329210

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