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Article

A novel KIF5B-ALK variant in nonsmall cell lung cancer.

Cancer - 15 Jun 2011

Wong Daisy Wing-Sze, Leung Elaine Lai-Han, Wong Sunny Kit-Man, Tin Vicky Pui-Chi, Sihoe Alan Dart-Loon, Cheng Lik-Cheung, Au Joseph Siu-Kie, Chung Lap-Ping, Wong Maria Pik

Abstract excerpt

BACKGROUND: The anaplastic lymphoma kinase (ALK) gene is involved frequently in chromosomal translocations, resulting in fusion genes with different partners found in various lymphoproliferative conditions. It was recently reported in nonsmall cell lung cancer (NSCLC) that the fusion protein encoded by echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) fusion gene conferred oncogenic properties. The...

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Topics

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Share to Adenocarcinoma
Share to Anaplastic Lymphoma Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Kinesins

Share to Neoplasm Invasiveness

Share to Oncogene Proteins, Fusion

Share to Receptor Protein-Tyrosine Kinases

Share to Translocation, Genetic

Source

Identifiers

PMID: 21656749
DOI: 10.1002/cncr.25843

Genes

ALK
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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