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Article

Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung Cancer.

Neoplasia (New York, N.Y.) - 1 Aug 2018

Gow Chien-Hung, Liu Yi-Nan, Li Huei-Ying, Hsieh Min-Shu, Chang Shih-Han, Luo Sheng-Ching, Tsai Tzu-Hsiu, Chen Pei-Lung, Tsai Meng-Feng, Shih Jin-Yuan

Abstract excerpt

A kinesin family member 5b (KIF5B)-MET proto-oncogene, receptor tyrosine kinase (MET) rearrangement was reported in patients with lung adenocarcinoma but its oncogenic function was not fully evaluated. We used one-step reverse transcription-polymerase chain reaction for RNA samples to screen for the KIF5B-MET fusion in 206 lung adenocarcinoma and 28 pulmonary sarcomatoid carcinoma patients. Genomic breakpoints of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30015159
DOI: 10.1016/j.neo.2018.06.007
PMCID: PMC6068088

Genes

MET
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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