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Article

ALK‐ rearrangement in non‐small‐cell lung cancer (NSCLC)

28 Feb 2018

Abstract excerpt

The ALK gene encodes a transmembrane tyrosine kinase receptor. ALK is physiologically expressed in the nervous system during embryogenesis, but its expression decreases postnatally. ALK first emerged in the field of oncology in 1994 when it was identified to fuse to NPM1 in anaplastic large-cell lymphoma. Since then, ALK has been associated with other types of cancers, including non-small-cell lung cancer...

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Identifiers

PMID: 29488330
DOI: 10.1111/1759-7714.12613

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