Article
SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients.
Genes and immunity - 1 Oct 2011
McElroy J P, Isobe N, Gourraud P A, Caillier S J, Matsushita T, Kohriyama T, Miyamoto K, Nakatsuji Y, Miki T, Hauser S L, Oksenberg J R, Kira J
Abstract excerpt
Although several major histocompatibility complex (MHC)-wide single-nucleotide polymorphism (SNP) studies have been performed in populations of European descent, none have been performed in Asian populations. The objective of this study was to identify human leukocyte antigen (HLA) loci associated with multiple sclerosis (MS) in a Japanese population genotyped for 3534 MHC region SNPs. Using a logistic regression...
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