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Article

Association Analysis Between HLA-DQA1 Loci and Neuromyelitis Optica Spectrum Disorder in a Han Chinese Population.

The neurologist - 1 Jul 2022

Zhou Lili, He Zhiyong, Zhu Lanbing, Zhu Juan-Juan, Zhu Jian-Hong, Pan Jialin

Abstract excerpt

BACKGROUND: Genome-wide association studies for neuromyelitis optica spectrum disorder (NMOSD) have established an association between HLA-DQ alpha 1 (DQA1) and risk for NMOSD. Though ethnicity is generally considered a major influencing factor in genetic analyses, little is known regarding the association of HLA-DQA1 polymorphisms with NMOSD in the Han population, especially the single-nucleotide polymorphisms...

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Identifiers

PMID: 34873111
DOI: 10.1097/NRL.0000000000000394
PMCID: PMC9257051

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