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Article

tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration

8 Jun 2011

Abstract excerpt

Recent lineage-tracing studies have produced conflicting results about whether the epicardium is a source of cardiac muscle cells during heart development. Here, we examined the developmental potential of epicardial tissue in zebrafish during both embryonic development and injury-induced heart regeneration. We found that upstream sequences of the transcription factor gene tcf21 activated robust,...

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PMID: 21653610
DOI: 10.1242/dev.067041

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