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Article

Transcriptional Control of Cell Lineage Development in Epicardium-Derived Cells

3 Jul 2013

Abstract excerpt

Epicardial derivatives, including vascular smooth muscle cells and cardiac fibroblasts, are crucial for proper development of the coronary vasculature and cardiac fibrous matrix, both of which support myocardial integrity and function in the normal heart. Epicardial formation, epithelial-to-mesenchymal transition (EMT), and epicardium-derived cell (EPDC) differentiation are precisely regulated by complex...

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Share to Cardiac Fibrosis and Remodeling
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PMID: 27840808
DOI: 10.3390/jdb1020092

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