Article
Submerged conidiation and product formation by Aspergillus niger at low specific growth rates are affected in aerial developmental mutants.
Applied and environmental microbiology - 1 Aug 2011
Jørgensen Thomas R, Nielsen Kristian F, Arentshorst Mark, Park Joohae, van den Hondel Cees A, Frisvad Jens C, Ram Arthur F
Abstract excerpt
Exposure to an aerial environment or severe nutrient limitation induces asexual differentiation in filamentous fungi. Submerged cultivation of Aspergillus niger in carbon- and energy-limited retentostat cultures both induces and fuels conidiation. Physiological and transcriptomic analyses have revealed that this differentiation strongly affects product formation. Since conidiation is inherent in the aerial...
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