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Article

Proteomic Analysis of Anti-Cancerous Scopularide Production by a Marine Microascus brevicaulis Strain and Its UV Mutant.

PloS one - 1 Jan 2015

Kramer Annemarie, Beck Hans Christian, Kumar Abhishek, Kristensen Lars Peter, Imhoff Johannes F, Labes Antje

Abstract excerpt

The marine fungus Microascus brevicaulis strain LF580 is a non-model secondary metabolite producer with high yields of the two secondary metabolites scopularides A and B, which exhibit distinct activities against tumour cell lines. A mutant strain was obtained using UV mutagenesis, showing faster growth and differences in pellet formation besides higher production levels. Here, we show the first proteome study of...

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Identifiers

PMID: 26460745
DOI: 10.1371/journal.pone.0140047
PMCID: PMC4603891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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