Article
Systems approaches to predict the functions of glycoside hydrolases during the life cycle of Aspergillus niger using developmental mutants ∆brlA and ∆flbA.
PloS one - 1 Jan 2015
van Munster Jolanda M, Nitsche Benjamin M, Akeroyd Michiel, Dijkhuizen Lubbert, van der Maarel Marc J E C, Ram Arthur F J
Abstract excerpt
BACKGROUND: The filamentous fungus Aspergillus niger encounters carbon starvation in nature as well as during industrial fermentations. In response, regulatory networks initiate and control autolysis and sporulation. Carbohydrate-active enzymes play an important role in these processes, for example by modifying cell walls during spore cell wall biogenesis or in cell wall degradation connected to autolysis....
Topics
- Aspergillus niger
- Bioreactors
- Carbohydrates
- Cell Wall
- Fermentation
- Fungal Proteins
- Gene Deletion
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Glycogen
- Glycoside Hydrolases
- Hydrolysis
- Mutation