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Article

The role for microRNAs in drug toxicity and in safety assessment

5 Mar 2015

Abstract excerpt

INTRODUCTION: Adverse drug reactions present significant challenges that impact pharmaceutical development and are major burdens to public health services worldwide. In response to this need, the field of toxicology is rapidly expanding to identify key pathways involved in drug toxicity. AREAS COVERED: MicroRNAs (miRNAs) are a class of small evolutionary conserved endogenous non-coding RNAs that regulate the...

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PMID: 25739314
DOI: 10.1517/17425255.2015.1021687

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