Allograft transplantation for Drosophila tumor metastasis studies.

Abstract excerpt

Drosophila has long been a powerful model for cancer research, yet the development of robust metastatic tumor models remains a challenge. Although allograft transplantation offers a promising approach, its use has been limited by technical constraints. Here, we established a reproducible serial transplantation protocol using lgl mutant brain tumors, enabling exponential expansion of tumor material and precise...

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