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Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection

2023-09-12

Abstract excerpt

<h4>ABSTRACT</h4> Malignant testicular germ cells tumors (TGCTs) are the most common solid cancers in young men. Current TGCT diagnostics include conventional serum protein markers, but these lack the sensitivity and specificity to serve as accurate markers across all TGCT subtypes. MicroRNAs (miRNAs) are small non-coding regulatory RNAs and informative biomarkers for several diseases. In humans, miRNAs of the mi...

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Literature Corpus work
ccb12021-2374-5d03-b027-d1f4a68db3bb
DOI
10.1101/2023.09.09.556995
Open publication

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Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detectionDOI 10.1101/2023.09.09.556995
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