Article
Mutator dynamics in sexual and asexual experimental populations of yeast.
BMC evolutionary biology - 7 Jun 2011
Raynes Yevgeniy, Gazzara Matthew R, Sniegowski Paul D
Abstract excerpt
BACKGROUND: In asexual populations, mutators may be expected to hitchhike with associated beneficial mutations. In sexual populations, recombination is predicted to erode such associations, inhibiting mutator hitchhiking. To investigate the effect of recombination on mutators experimentally, we compared the frequency dynamics of a mutator allele (msh2Δ) in sexual and asexual populations of Saccharomyces...
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