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Epigenetic reprogramming throughout preimplantation development and consequences for assisted reproductive technologies

1 Mar 2005

Abstract excerpt

Knowledge about preimplantation development is important both for basic reproductive biology and for practical applications, including livestock breeding and regenerative medicine. During preimplantation development, epigenetic modifications such as DNA methylation and histone modifications are involved in the regulation of imprinted and non-imprinted genes, in the initiation of X chromosome inactivation, and the...

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PMID: 15838918
DOI: 10.1002/bdrc.20035

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