Article
Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.
The EMBO journal - 1 Jan 1991
Zelent A, Mendelsohn C, Kastner P, Krust A, Garnier J M, Ruffenach F, Leroy P, Chambon P
Abstract excerpt
Using anchored PCR, three different cDNA isoforms of the mouse retinoic acid receptor beta [mRAR-beta 1, mRAR-beta 2 (formerly mRAR-beta 0) and mRAR-beta 3], generated from the same gene by differential promoter usage and alternative splicing, were isolated. These three isoforms encode RAR proteins with different N-terminal A regions and identical B - F regions. The sequence encoding the first 59 amino acids of...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- DNA
- Exons
- Genetic Variation
- Humans
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
