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Article

Mutational analysis of the promoter region of the alpha 27 gene of herpes simplex virus 1 within the context of the viral genome.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990

Spector D, Purves F, Roizman B

Abstract excerpt

In herpes simplex virus 1-infected cells, the first set of genes to be expressed (alpha genes) is induced by the alpha gene trans-inducing factor (alpha TIF), a virion structural protein. The cis-acting site in the 5' untranscribed domain of alpha genes was previously reported to be the sequence...

Topics

Animals
Base Sequence
Cloning, Molecular
Genes, Viral
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Restriction Mapping
Simplexvirus
Vero Cells
Viral Structural Proteins

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Identifiers

PMID: 2164672
DOI: 10.1073/pnas.87.14.5268
PMCID: PMC54304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2164672-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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