Article
The gene for 16S rRNA methyltransferase (ksgA) functions as a multicopy suppressor for a cold-sensitive mutant of era, an essential RAS-like GTP-binding protein in Escherichia coli.
Journal of bacteriology - 1 Oct 1998
Lu Q, Inouye M
Abstract excerpt
Era, a Ras-like GTP-binding protein in Escherichia coli, has been shown to be essential for growth. However, its cellular functions still remain elusive. In this study, a genetic screening of an E. coli genomic library was performed to identify those genes which can restore the growth ability of...
Topics
- Chromosome Mapping
- Cloning, Molecular
- Cold Temperature
- Escherichia coli
- Escherichia coli Proteins
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Genes, Bacterial
- Genes, Suppressor
- Methyltransferases
- Mutation
- RNA-Binding Proteins